mercaptopurine (Meaning)
Wordnet
mercaptopurine (n)
a drug (trade name Purinethol) that interferes with the metabolism of purine and is used to treat acute lymphocytic leukemia
Synonyms & Antonyms of mercaptopurine
No Synonyms and anytonyms found
mercaptopurine Sentence Examples
- Mercaptopurine is a purine analog used as an immunosuppressant in the treatment of leukemia.
- The efficacy of mercaptopurine is influenced by genetic variations in the TPMT enzyme.
- Mercaptopurine is metabolized in the liver by the enzyme thiopurine methyltransferase (TPMT).
- Patients with a deficiency in TPMT activity are at a higher risk of severe adverse effects from mercaptopurine.
- Mercaptopurine can cause myelosuppression, including neutropenia, anemia, and thrombocytopenia.
- Other potential adverse effects of mercaptopurine include hepatotoxicity, nausea, and vomiting.
- Mercaptopurine is typically administered orally, but can also be given intravenously.
- The dosage of mercaptopurine is individualized based on patient factors such as TPMT status and disease severity.
- Regular monitoring of blood counts and liver function is recommended during mercaptopurine therapy.
- Mercaptopurine has been shown to increase the risk of developing secondary malignancies.
FAQs About the word mercaptopurine
a drug (trade name Purinethol) that interferes with the metabolism of purine and is used to treat acute lymphocytic leukemia
No synonyms found.
No antonyms found.
Mercaptopurine is a purine analog used as an immunosuppressant in the treatment of leukemia.
The efficacy of mercaptopurine is influenced by genetic variations in the TPMT enzyme.
Mercaptopurine is metabolized in the liver by the enzyme thiopurine methyltransferase (TPMT).
Patients with a deficiency in TPMT activity are at a higher risk of severe adverse effects from mercaptopurine.
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