cystic fibrosis transport regulator (Meaning)
Wordnet
cystic fibrosis transport regulator (n)
the gene that is mutated in cystic fibrosis
Synonyms & Antonyms of cystic fibrosis transport regulator
No Synonyms and anytonyms found
cystic fibrosis transport regulator Sentence Examples
- The cystic fibrosis transmembrane conductance regulator (CFTR) is a protein that regulates the movement of chloride ions across cell membranes.
- Mutations in the CFTR gene can lead to cystic fibrosis, a genetic disorder characterized by dysfunctional chloride transport.
- The CFTR protein acts as a channel for chloride ions, playing a crucial role in maintaining the balance of salt and water in various tissues.
- Dysfunction of the CFTR protein in cystic fibrosis results in the production of thick, sticky mucus that obstructs the airways and affects the function of other organs.
- CFTR modulator therapies, such as ivacaftor and lumacaftor/ivacaftor, target specific mutations in the CFTR gene to improve chloride transport and alleviate symptoms of cystic fibrosis.
- The discovery of the CFTR gene and its role in cystic fibrosis has revolutionized our understanding and treatment of the disease.
- CFTR modulators work by enhancing the function of defective CFTR proteins, thereby restoring chloride transport across cell membranes.
- The development of CFTR modulator therapies has led to significant improvements in lung function, quality of life, and life expectancy for individuals with cystic fibrosis.
- Genetic testing is used to identify specific CFTR mutations in individuals with cystic fibrosis, guiding the selection of appropriate treatment options.
- Research continues to explore new strategies for targeting the CFTR protein to further improve outcomes for individuals living with cystic fibrosis.
FAQs About the word cystic fibrosis transport regulator
the gene that is mutated in cystic fibrosis
No synonyms found.
No antonyms found.
The cystic fibrosis transmembrane conductance regulator (CFTR) is a protein that regulates the movement of chloride ions across cell membranes.
Mutations in the CFTR gene can lead to cystic fibrosis, a genetic disorder characterized by dysfunctional chloride transport.
The CFTR protein acts as a channel for chloride ions, playing a crucial role in maintaining the balance of salt and water in various tissues.
Dysfunction of the CFTR protein in cystic fibrosis results in the production of thick, sticky mucus that obstructs the airways and affects the function of other organs.
