cyclooxygenase-2 (Meaning)

Wordnet

cyclooxygenase-2 (n)

an enzyme that makes prostaglandins that cause inflammation and pain and fever

No Synonyms and anytonyms found

Cyclooxygenase-2 (COX-2) is an inducible enzyme involved in the synthesis of prostaglandins during inflammation.
Unlike cyclooxygenase-1 (COX-1), COX-2 expression is upregulated in response to inflammatory stimuli.
COX-2 plays a pivotal role in mediating pain, fever, and inflammation in various tissues.
Selective inhibitors of COX-2 have been developed to alleviate pain and inflammation without affecting the gastrointestinal tract.
COX-2 inhibitors are commonly prescribed for conditions such as osteoarthritis and rheumatoid arthritis.
COX-2-derived prostaglandins contribute to the pathogenesis of inflammatory diseases by promoting vasodilation and increasing vascular permeability.
Overexpression of COX-2 has been observed in several types of cancer, suggesting its involvement in tumor growth and progression.
COX-2 inhibitors have shown promise in cancer therapy by inhibiting angiogenesis and enhancing the efficacy of chemotherapy.
Research on COX-2 regulation and function continues to uncover its role in various physiological and pathological processes.
Understanding the molecular mechanisms underlying COX-2 activity is essential for the development of targeted therapies for inflammatory and neoplastic disorders.

an enzyme that makes prostaglandins that cause inflammation and pain and fever

No synonyms found.

No antonyms found.

Cyclooxygenase-2 (COX-2) is an inducible enzyme involved in the synthesis of prostaglandins during inflammation.

Unlike cyclooxygenase-1 (COX-1), COX-2 expression is upregulated in response to inflammatory stimuli.

COX-2 plays a pivotal role in mediating pain, fever, and inflammation in various tissues.

Selective inhibitors of COX-2 have been developed to alleviate pain and inflammation without affecting the gastrointestinal tract.