cyclooxygenase-2 Synonyms
No Synonyms and anytonyms found
cyclooxygenase-2 Meaning
Wordnet
cyclooxygenase-2 (n)
an enzyme that makes prostaglandins that cause inflammation and pain and fever
cyclooxygenase-2 Sentence Examples
- Cyclooxygenase-2 (COX-2) is an inducible enzyme involved in the synthesis of prostaglandins during inflammation.
- Unlike cyclooxygenase-1 (COX-1), COX-2 expression is upregulated in response to inflammatory stimuli.
- COX-2 plays a pivotal role in mediating pain, fever, and inflammation in various tissues.
- Selective inhibitors of COX-2 have been developed to alleviate pain and inflammation without affecting the gastrointestinal tract.
- COX-2 inhibitors are commonly prescribed for conditions such as osteoarthritis and rheumatoid arthritis.
- COX-2-derived prostaglandins contribute to the pathogenesis of inflammatory diseases by promoting vasodilation and increasing vascular permeability.
- Overexpression of COX-2 has been observed in several types of cancer, suggesting its involvement in tumor growth and progression.
- COX-2 inhibitors have shown promise in cancer therapy by inhibiting angiogenesis and enhancing the efficacy of chemotherapy.
- Research on COX-2 regulation and function continues to uncover its role in various physiological and pathological processes.
- Understanding the molecular mechanisms underlying COX-2 activity is essential for the development of targeted therapies for inflammatory and neoplastic disorders.
FAQs About the word cyclooxygenase-2
an enzyme that makes prostaglandins that cause inflammation and pain and fever
No synonyms found.
No antonyms found.
Cyclooxygenase-2 (COX-2) is an inducible enzyme involved in the synthesis of prostaglandins during inflammation.
Unlike cyclooxygenase-1 (COX-1), COX-2 expression is upregulated in response to inflammatory stimuli.
COX-2 plays a pivotal role in mediating pain, fever, and inflammation in various tissues.
Selective inhibitors of COX-2 have been developed to alleviate pain and inflammation without affecting the gastrointestinal tract.