beta-lactamase (Meaning)
beta-lactamase (n)
enzyme produced by certain bacteria that inactivates penicillin and results in resistance to that antibiotic
Synonyms & Antonyms of beta-lactamase
No Synonyms and anytonyms found
beta-lactamase Sentence Examples
- Beta-lactamase production is a major mechanism of bacterial resistance to beta-lactam antibiotics.
- The presence of beta-lactamase can render bacteria resistant to penicillin and other beta-lactam drugs.
- Extended-spectrum beta-lactamase (ESBL) enzymes can hydrolyze a wider range of beta-lactams than classical beta-lactamases.
- Carbapenemases, a type of beta-lactamase, can confer resistance to carbapenems, last-line antibiotics often used against multidrug-resistant bacteria.
- Beta-lactamase inhibitors, such as clavulanic acid and tazobactam, can prevent beta-lactam hydrolysis and restore antibiotic efficacy.
- Researchers are actively developing new beta-lactamase inhibitors to overcome antibiotic resistance.
- Beta-lactamase detection is crucial for guiding appropriate antibiotic selection in clinical settings.
- Extended-spectrum beta-lactamase-producing organisms (ESBLOs) pose a significant public health threat due to their resistance to multiple antibiotics.
- The emergence of beta-lactamase-mediated resistance is a growing challenge in antimicrobial stewardship.
- Beta-lactamase testing is recommended for suspected infections caused by multidrug-resistant bacteria.
FAQs About the word beta-lactamase
enzyme produced by certain bacteria that inactivates penicillin and results in resistance to that antibiotic
No synonyms found.
No antonyms found.
Beta-lactamase production is a major mechanism of bacterial resistance to beta-lactam antibiotics.
The presence of beta-lactamase can render bacteria resistant to penicillin and other beta-lactam drugs.
Extended-spectrum beta-lactamase (ESBL) enzymes can hydrolyze a wider range of beta-lactams than classical beta-lactamases.
Carbapenemases, a type of beta-lactamase, can confer resistance to carbapenems, last-line antibiotics often used against multidrug-resistant bacteria.
