beta-lactamase Synonyms

No Synonyms and anytonyms found

beta-lactamase Meaning

Wordnet

beta-lactamase (n)

enzyme produced by certain bacteria that inactivates penicillin and results in resistance to that antibiotic

beta-lactamase Sentence Examples

  1. Beta-lactamase production is a major mechanism of bacterial resistance to beta-lactam antibiotics.
  2. The presence of beta-lactamase can render bacteria resistant to penicillin and other beta-lactam drugs.
  3. Extended-spectrum beta-lactamase (ESBL) enzymes can hydrolyze a wider range of beta-lactams than classical beta-lactamases.
  4. Carbapenemases, a type of beta-lactamase, can confer resistance to carbapenems, last-line antibiotics often used against multidrug-resistant bacteria.
  5. Beta-lactamase inhibitors, such as clavulanic acid and tazobactam, can prevent beta-lactam hydrolysis and restore antibiotic efficacy.
  6. Researchers are actively developing new beta-lactamase inhibitors to overcome antibiotic resistance.
  7. Beta-lactamase detection is crucial for guiding appropriate antibiotic selection in clinical settings.
  8. Extended-spectrum beta-lactamase-producing organisms (ESBLOs) pose a significant public health threat due to their resistance to multiple antibiotics.
  9. The emergence of beta-lactamase-mediated resistance is a growing challenge in antimicrobial stewardship.
  10. Beta-lactamase testing is recommended for suspected infections caused by multidrug-resistant bacteria.

FAQs About the word beta-lactamase

enzyme produced by certain bacteria that inactivates penicillin and results in resistance to that antibiotic

No synonyms found.

No antonyms found.

Beta-lactamase production is a major mechanism of bacterial resistance to beta-lactam antibiotics.

The presence of beta-lactamase can render bacteria resistant to penicillin and other beta-lactam drugs.

Extended-spectrum beta-lactamase (ESBL) enzymes can hydrolyze a wider range of beta-lactams than classical beta-lactamases.

Carbapenemases, a type of beta-lactamase, can confer resistance to carbapenems, last-line antibiotics often used against multidrug-resistant bacteria.