gamma-interferon Antonyms
No Synonyms and anytonyms found
Meaning of gamma-interferon
Wordnet
gamma-interferon (n)
a form of interferon that is produced by T cells and macrophages; involved in the activation of phagocytes
gamma-interferon Sentence Examples
- Gamma-interferon (IFN-γ) plays a crucial role in the cellular immune response against viral and bacterial infections.
- IFN-γ is produced by activated T cells and natural killer cells in response to specific antigens.
- It enhances the expression of MHC class I and II molecules on target cells, making them more recognizable to cytotoxic T cells.
- IFN-γ promotes macrophage activation and polarization towards a pro-inflammatory M1 phenotype.
- Its antiviral effects are mediated by the induction of STAT1 phosphorylation and the upregulation of antiviral proteins.
- IFN-γ also exhibits antitumor activity by inhibiting cell proliferation, inducing apoptosis, and promoting immune surveillance.
- Dysregulation of IFN-γ production is associated with various autoimmune diseases, including multiple sclerosis, rheumatoid arthritis, and type 1 diabetes.
- Recombinant IFN-γ is used therapeutically to treat certain chronic granulomatous diseases and severe viral infections.
- The gamma-interferon release assay (IGRA) is a diagnostic tool for detecting latent tuberculosis infection.
- Continued research on IFN-γ's molecular mechanisms and clinical applications is essential for advancing our understanding of immune-mediated diseases and developing novel therapies.
FAQs About the word gamma-interferon
a form of interferon that is produced by T cells and macrophages; involved in the activation of phagocytes
No synonyms found.
No antonyms found.
Gamma-interferon (IFN-γ) plays a crucial role in the cellular immune response against viral and bacterial infections.
IFN-γ is produced by activated T cells and natural killer cells in response to specific antigens.
It enhances the expression of MHC class I and II molecules on target cells, making them more recognizable to cytotoxic T cells.
IFN-γ promotes macrophage activation and polarization towards a pro-inflammatory M1 phenotype.
