vinblastine Synonyms
No Synonyms and anytonyms found
vinblastine Meaning
Wordnet
vinblastine (n)
periwinkle plant derivative used as an antineoplastic drug (trade name Velban) that disrupts cell division
vinblastine Sentence Examples
- Vinblastine is an alkaloid extracted from the periwinkle plant, Catharanthus roseus.
- Vinblastine is a mitotic inhibitor, commonly used as a treatment for Hodgkin's lymphoma and other cancers.
- Due to its toxicity to rapidly dividing cells, vinblastine is also used in research on cell cycle regulation.
- Vinblastine has been shown to induce apoptosis in cancer cells by activating the mitochondrial pathway.
- The antitumor effects of vinblastine are primarily mediated by its interaction with the protein tubulin.
- Vinblastine is administered intravenously and exhibits a half-life of approximately 24 hours.
- Common side effects of vinblastine treatment include alopecia, nausea, and bone marrow suppression.
- Vinblastine is frequently used in combination with other chemotherapeutic agents to enhance efficacy and reduce resistance.
- Advances in drug delivery systems are being explored to improve the bioavailability and reduce the toxicity of vinblastine.
- Research efforts are underway to develop vinblastine analogs with improved pharmacological properties and reduced side effects.
FAQs About the word vinblastine
periwinkle plant derivative used as an antineoplastic drug (trade name Velban) that disrupts cell division
No synonyms found.
No antonyms found.
Vinblastine is an alkaloid extracted from the periwinkle plant, Catharanthus roseus.
Vinblastine is a mitotic inhibitor, commonly used as a treatment for Hodgkin's lymphoma and other cancers.
Due to its toxicity to rapidly dividing cells, vinblastine is also used in research on cell cycle regulation.
Vinblastine has been shown to induce apoptosis in cancer cells by activating the mitochondrial pathway.
