tumor necrosis factor Synonyms
No Synonyms and anytonyms found
tumor necrosis factor Meaning
tumor necrosis factor (n)
a proinflammatory cytokine that is produced by white blood cells (monocytes and macrophages); has an antineoplastic effect but causes inflammation (as in rheumatoid arthritis)
tumor necrosis factor Sentence Examples
- Tumor necrosis factor (TNF) is a key cytokine involved in the inflammatory response.
- TNF is produced by macrophages and other immune cells in response to various stimuli.
- TNF promotes the recruitment and activation of inflammatory cells, leading to tissue destruction.
- TNF can induce apoptosis and necrosis in tumor cells, contributing to tumor regression.
- TNF inhibitors are used to treat conditions characterized by chronic inflammation, such as rheumatoid arthritis.
- Excessive TNF production can lead to systemic inflammation and sepsis.
- Genetic polymorphisms in the TNF gene are associated with susceptibility to inflammatory diseases.
- TNF is a potent activator of the nuclear factor kappa B (NF-κB) signaling pathway.
- TNF-driven inflammation plays a role in the pathogenesis of neurodegenerative disorders.
- The role of TNF in cancer development and progression is complex and remains an active area of research.
FAQs About the word tumor necrosis factor
a proinflammatory cytokine that is produced by white blood cells (monocytes and macrophages); has an antineoplastic effect but causes inflammation (as in rheuma
No synonyms found.
No antonyms found.
Tumor necrosis factor (TNF) is a key cytokine involved in the inflammatory response.
TNF is produced by macrophages and other immune cells in response to various stimuli.
TNF promotes the recruitment and activation of inflammatory cells, leading to tissue destruction.
TNF can induce apoptosis and necrosis in tumor cells, contributing to tumor regression.
