tissue plasminogen activator Synonyms
No Synonyms and anytonyms found
tissue plasminogen activator Meaning
Wordnet
tissue plasminogen activator (n)
a thrombolytic agent (trade name Activase) that causes fibrinolysis at the site of a blood clot; used in treating acute myocardial infarction
tissue plasminogen activator Sentence Examples
- Tissue plasminogen activator (tPA) is a thrombolytic agent used to dissolve blood clots in the brain.
- tPA is produced by endothelial cells and other cells in the body.
- tPA converts plasminogen into plasmin, which breaks down fibrin, the major component of blood clots.
- tPA is typically administered intravenously to patients with ischemic stroke.
- tPA therapy is most effective when administered within three hours of stroke onset.
- tPA can cause side effects, including bleeding, intracranial hemorrhage, and allergic reactions.
- The use of tPA in stroke patients has been controversial, with some studies showing benefit and others showing no or even harmful effects.
- tPA is also being investigated as a potential treatment for other conditions, such as myocardial infarction and peripheral artery disease.
- Recombinant tPA (rtPA) is a genetically engineered form of tPA that is produced in the laboratory.
- rtPA is approved for the treatment of ischemic stroke in both the United States and Europe.
FAQs About the word tissue plasminogen activator
a thrombolytic agent (trade name Activase) that causes fibrinolysis at the site of a blood clot; used in treating acute myocardial infarction
No synonyms found.
No antonyms found.
Tissue plasminogen activator (tPA) is a thrombolytic agent used to dissolve blood clots in the brain.
tPA is produced by endothelial cells and other cells in the body.
tPA converts plasminogen into plasmin, which breaks down fibrin, the major component of blood clots.
tPA is typically administered intravenously to patients with ischemic stroke.
