thioguanine Synonyms
No Synonyms and anytonyms found
thioguanine Meaning
Wordnet
thioguanine (n)
an antineoplastic drug used to treat acute leukemias
thioguanine Sentence Examples
- Thioguanine is a purine analog commonly used in the treatment of acute myeloid leukemia.
- The mechanism of action of thioguanine involves the inhibition of DNA synthesis by interfering with nucleotide interconversion.
- Thioguanine is typically administered orally in combination with other chemotherapy agents.
- Dosage adjustments of thioguanine may be necessary based on individual patient factors, including body weight and underlying liver function.
- Common side effects of thioguanine include myelosuppression, gastrointestinal toxicity, and hepatotoxicity.
- Myelosuppression caused by thioguanine can lead to decreases in blood cell counts, including neutrophils, platelets, and red blood cells.
- Gastrointestinal toxicity associated with thioguanine can manifest as nausea, vomiting, and diarrhea.
- Liver enzymes should be monitored during thioguanine therapy to assess for potential hepatotoxicity.
- Resistance to thioguanine can develop over time, necessitating a change in treatment regimen.
- Alternative agents, such as mercaptopurine, may be considered if resistance to thioguanine develops.
FAQs About the word thioguanine
an antineoplastic drug used to treat acute leukemias
No synonyms found.
No antonyms found.
Thioguanine is a purine analog commonly used in the treatment of acute myeloid leukemia.
The mechanism of action of thioguanine involves the inhibition of DNA synthesis by interfering with nucleotide interconversion.
Thioguanine is typically administered orally in combination with other chemotherapy agents.
Dosage adjustments of thioguanine may be necessary based on individual patient factors, including body weight and underlying liver function.
