novobiocin Synonyms
No Synonyms and anytonyms found
novobiocin Meaning
Wordnet
novobiocin (n)
an antibiotic obtained from an actinomycete and used to treat infections by Gram-positive bacteria
novobiocin Sentence Examples
- Novobiocin is a bactericidal antibiotic commonly used against staphylococcal infections.
- The mechanism of action of novobiocin involves the inhibition of DNA gyrase, an enzyme crucial for bacterial DNA replication.
- Novobiocin exhibits excellent activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae.
- Resistance to novobiocin occurs primarily through mutations in the grlA gene, which encodes the DNA gyrase target.
- Novobiocin is administered orally or intravenously for the treatment of skin and soft tissue infections, osteomyelitis, and bacteremia.
- Novobiocin is generally well-tolerated, with common side effects including gastrointestinal disturbances and skin rashes.
- Novobiocin is contraindicated in individuals with known hypersensitivity to the drug or other coumarins.
- Novobiocin is not recommended for use during pregnancy or breastfeeding due to potential adverse effects on the fetus or infant.
- Novobiocin can interact with certain medications, including warfarin and other anticoagulants, increasing the risk of bleeding complications.
- Novobiocin is an important antibiotic for treating infections caused by Gram-positive bacteria, particularly in cases where methicillin-resistant Staphylococcus aureus (MRSA) is involved.
FAQs About the word novobiocin
an antibiotic obtained from an actinomycete and used to treat infections by Gram-positive bacteria
No synonyms found.
No antonyms found.
Novobiocin is a bactericidal antibiotic commonly used against staphylococcal infections.
The mechanism of action of novobiocin involves the inhibition of DNA gyrase, an enzyme crucial for bacterial DNA replication.
Novobiocin exhibits excellent activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae.
Resistance to novobiocin occurs primarily through mutations in the grlA gene, which encodes the DNA gyrase target.
