mutamycin Synonyms
No Synonyms and anytonyms found
mutamycin Meaning
mutamycin (n)
a complex of antibiotic substances obtained from a streptomyces bacterium; one form (trade name Mutamycin) shows promise as an anticancer drug
mutamycin Sentence Examples
- Mutamycin was discovered as an antibiotic that selectively inhibits DNA synthesis in bacteria and mammalian cells.
- Researchers have investigated the potential of mutamycin as a radiosensitizer to enhance the effectiveness of radiation therapy.
- Mutamycin binds to DNA and disrupts replication, leading to cell death or cell cycle arrest.
- The cytotoxicity of mutamycin is influenced by the cell cycle phase and the DNA repair capabilities of the cells.
- Mutamycin has demonstrated promising activity against various cancer cell lines, including those resistant to conventional chemotherapeutic agents.
- The clinical development of mutamycin has been hampered by its toxicity, which includes myelosuppression and gastrointestinal side effects.
- Modifications to the mutamycin structure have been pursued to improve its therapeutic window and reduce toxicity.
- Mutamycin analogs with improved pharmacological properties are currently being evaluated in preclinical and clinical studies.
- Combinations of mutamycin with other anticancer agents have shown enhanced antitumor activity in animal models.
- Further research is needed to fully elucidate the mechanisms of action and potential clinical applications of mutamycin and its derivatives.
FAQs About the word mutamycin
a complex of antibiotic substances obtained from a streptomyces bacterium; one form (trade name Mutamycin) shows promise as an anticancer drug
No synonyms found.
No antonyms found.
Mutamycin was discovered as an antibiotic that selectively inhibits DNA synthesis in bacteria and mammalian cells.
Researchers have investigated the potential of mutamycin as a radiosensitizer to enhance the effectiveness of radiation therapy.
Mutamycin binds to DNA and disrupts replication, leading to cell death or cell cycle arrest.
The cytotoxicity of mutamycin is influenced by the cell cycle phase and the DNA repair capabilities of the cells.
