tumour necrosis factor (Meaning)
tumour necrosis factor (n)
a proinflammatory cytokine that is produced by white blood cells (monocytes and macrophages); has an antineoplastic effect but causes inflammation (as in rheumatoid arthritis)
Synonyms & Antonyms of tumour necrosis factor
No Synonyms and anytonyms found
tumour necrosis factor Sentence Examples
- Tumour necrosis factor alpha (TNF-α) is a potent cytokine that plays a crucial role in the inflammatory response.
- TNF-α can induce apoptosis, or programmed cell death, in susceptible cells.
- Elevated levels of TNF-α have been implicated in a wide range of inflammatory diseases, including rheumatoid arthritis and inflammatory bowel disease.
- TNF-α inhibitors are a class of drugs used to treat inflammatory diseases by blocking the activity of TNF-α.
- TNF-α is involved in the regulation of the immune response, and its dysregulation can contribute to autoimmune disorders.
- TNF-α can activate endothelial cells and promote angiogenesis, the formation of new blood vessels.
- The production of TNF-α is tightly regulated by a complex network of signalling pathways.
- TNF-α can act as a pro-inflammatory cytokine and can contribute to tissue damage in chronic inflammatory diseases.
- TNF-α is also involved in the pathogenesis of cancer, where it can promote tumour growth and metastasis.
- Research is ongoing to develop novel TNF-α inhibitors for the treatment of inflammatory diseases and cancer.
FAQs About the word tumour necrosis factor
a proinflammatory cytokine that is produced by white blood cells (monocytes and macrophages); has an antineoplastic effect but causes inflammation (as in rheuma
No synonyms found.
No antonyms found.
Tumour necrosis factor alpha (TNF-α) is a potent cytokine that plays a crucial role in the inflammatory response.
TNF-α can induce apoptosis, or programmed cell death, in susceptible cells.
Elevated levels of TNF-α have been implicated in a wide range of inflammatory diseases, including rheumatoid arthritis and inflammatory bowel disease.
TNF-α inhibitors are a class of drugs used to treat inflammatory diseases by blocking the activity of TNF-α.
