thyrotropin-releasing factor (Meaning)
thyrotropin-releasing factor (n)
hormone released by the hypothalamus that controls the release of thyroid-stimulating hormone from the anterior pituitary
Synonyms & Antonyms of thyrotropin-releasing factor
No Synonyms and anytonyms found
thyrotropin-releasing factor Sentence Examples
- Thyrotropin-releasing factor (TRF), also known as thyrotropin-releasing hormone, stimulates the release of thyroid-stimulating hormone (TSH) from the anterior pituitary gland.
- TRF is a polypeptide hormone produced by the hypothalamus that plays a crucial role in the regulation of thyroid hormone production.
- When thyroid hormone levels in the blood decrease, TRF secretion is increased, triggering the release of TSH, which in turn stimulates the thyroid gland to produce more thyroid hormone.
- Conversely, when thyroid hormone levels are elevated, TRF production decreases, inhibiting TSH release and thyroid hormone synthesis.
- TRF exerts its effects on the pituitary gland by binding to specific receptors on the surface of thyrotropes, which are cells responsible for producing TSH.
- The release of TRF is influenced by various factors, including the availability of thyroid hormones and certain neurotransmitters.
- TRF deficiency can lead to hypothyroidism, a condition characterized by low thyroid hormone levels, while excessive TRF secretion can cause hyperthyroidism, a condition with elevated thyroid hormone levels.
- Medications that inhibit TRF secretion can be used to treat hyperthyroidism, while TRF replacement therapy may be necessary for individuals with TRF deficiency.
- Animal studies have demonstrated that altering TRF levels can affect body weight, metabolism, and reproductive function.
- Further research on TRF and its role in regulating thyroid function and other physiological processes may lead to new insights and therapeutic interventions.
FAQs About the word thyrotropin-releasing factor
hormone released by the hypothalamus that controls the release of thyroid-stimulating hormone from the anterior pituitary
No synonyms found.
No antonyms found.
Thyrotropin-releasing factor (TRF), also known as thyrotropin-releasing hormone, stimulates the release of thyroid-stimulating hormone (TSH) from the anterior pituitary gland.
TRF is a polypeptide hormone produced by the hypothalamus that plays a crucial role in the regulation of thyroid hormone production.
When thyroid hormone levels in the blood decrease, TRF secretion is increased, triggering the release of TSH, which in turn stimulates the thyroid gland to produce more thyroid hormone.
Conversely, when thyroid hormone levels are elevated, TRF production decreases, inhibiting TSH release and thyroid hormone synthesis.
