suppressor gene (Meaning)
Wordnet
suppressor gene (n)
a gene that suppresses the phenotypic expression of another gene (especially of a mutant gene)
Synonyms & Antonyms of suppressor gene
No Synonyms and anytonyms found
suppressor gene Sentence Examples
- While oncogenes promote uncontrolled cell growth, suppressor genes act as a counterbalance to prevent cancerous mutations.
- The TP53 gene is a key suppressor gene that plays a crucial role in cell cycle regulation and apoptosis.
- Defects or mutations in suppressor genes can lead to the loss of their protective function, contributing to the development of cancer.
- BRCA1 and BRCA2 are well-known suppressor genes that are associated with an increased risk of breast and ovarian cancers.
- By understanding the mechanisms of suppressor genes, researchers aim to develop new therapeutic strategies for treating cancer.
- The inactivation of suppressor genes can occur through various genetic alterations, including mutations, deletions, or epigenetic modifications.
- Tumors with defective suppressor genes often exhibit faster growth and increased resistance to radiation and chemotherapy.
- Overcoming the suppression of oncogenes by activating suppressor genes is a promising approach in cancer therapy.
- Germline mutations in certain suppressor genes can result in inherited cancer syndromes, such as Li-Fraumeni syndrome.
- The discovery and study of suppressor genes have revolutionized our understanding of cancer development and have paved the way for targeted cancer treatments.
FAQs About the word suppressor gene
a gene that suppresses the phenotypic expression of another gene (especially of a mutant gene)
No synonyms found.
No antonyms found.
While oncogenes promote uncontrolled cell growth, suppressor genes act as a counterbalance to prevent cancerous mutations.
The TP53 gene is a key suppressor gene that plays a crucial role in cell cycle regulation and apoptosis.
Defects or mutations in suppressor genes can lead to the loss of their protective function, contributing to the development of cancer.
BRCA1 and BRCA2 are well-known suppressor genes that are associated with an increased risk of breast and ovarian cancers.
