rofecoxib (Meaning)
rofecoxib (n)
a Cox-2 inhibitor (trade name Vioxx) that relieves pain and inflammation without harming the digestive tract; voluntarily withdrawn from the market in 2004
Synonyms & Antonyms of rofecoxib
No Synonyms and anytonyms found
rofecoxib Sentence Examples
- Rofecoxib was a prescription drug belonging to the class of nonsteroidal anti-inflammatory drugs (NSAIDs).
- Introduced in 1999, rofecoxib was used to treat various musculoskeletal conditions, including arthritis and menstrual cramps.
- In 2004, rofecoxib was withdrawn from the market after studies linked it to an increased risk of cardiovascular events.
- The withdrawal of rofecoxib raised concerns about the safety of other COX-2 inhibitors.
- Rofecoxib was primarily marketed under the brand name Vioxx.
- The mechanism of action of rofecoxib involved inhibiting the enzyme cyclooxygenase-2 (COX-2).
- Rofecoxib is a potent NSAID with analgesic, anti-inflammatory, and antipyretic properties.
- The use of rofecoxib was associated with an increased risk of heart attack and stroke, particularly in patients with underlying cardiovascular disease.
- The discontinuation of rofecoxib led to a significant decrease in the number of cardiovascular events reported.
- The case of rofecoxib is a reminder of the importance of rigorous drug monitoring and post-market evaluation.
FAQs About the word rofecoxib
a Cox-2 inhibitor (trade name Vioxx) that relieves pain and inflammation without harming the digestive tract; voluntarily withdrawn from the market in 2004
No synonyms found.
No antonyms found.
Rofecoxib was a prescription drug belonging to the class of nonsteroidal anti-inflammatory drugs (NSAIDs).
Introduced in 1999, rofecoxib was used to treat various musculoskeletal conditions, including arthritis and menstrual cramps.
In 2004, rofecoxib was withdrawn from the market after studies linked it to an increased risk of cardiovascular events.
The withdrawal of rofecoxib raised concerns about the safety of other COX-2 inhibitors.
