plasminogen (Meaning)
Wordnet
plasminogen (n)
an inactive form of plasmin that occurs in plasma and is converted to plasmin by organic solvents
Synonyms & Antonyms of plasminogen
No Synonyms and anytonyms found
plasminogen Sentence Examples
- Plasminogen is a zymogen that is converted to the active enzyme plasmin through a series of proteolytic events.
- Plasminogen is synthesized in the liver and circulates in the blood as an inactive precursor.
- The conversion of plasminogen to plasmin is initiated by tissue plasminogen activator (tPA) or urokinase plasminogen activator (uPA).
- Plasminogen activators bind to plasminogen and cleave a specific peptide bond, exposing a cryptic active site.
- Once activated, plasmin cleaves fibrin clots, which facilitates clot lysis and bleeding.
- Plasminogen deficiency can lead to impaired fibrinolysis and an increased risk of thrombosis.
- Plasminogen activator inhibitors (PAIs) regulate the activity of plasminogen activators and prevent excessive fibrinolysis.
- Dysregulation of the plasminogen-plasmin system has been implicated in a variety of diseases, including cardiovascular disease and cancer.
- Plasminogen can be activated by both enzymatic and non-enzymatic pathways.
- The plasminogen-plasmin system plays a crucial role in maintaining vascular patency and tissue homeostasis.
FAQs About the word plasminogen
an inactive form of plasmin that occurs in plasma and is converted to plasmin by organic solvents
No synonyms found.
No antonyms found.
Plasminogen is a zymogen that is converted to the active enzyme plasmin through a series of proteolytic events.
Plasminogen is synthesized in the liver and circulates in the blood as an inactive precursor.
The conversion of plasminogen to plasmin is initiated by tissue plasminogen activator (tPA) or urokinase plasminogen activator (uPA).
Plasminogen activators bind to plasminogen and cleave a specific peptide bond, exposing a cryptic active site.
