oxaloacetate (Meaning)
Wordnet
oxaloacetate (n)
a salt or ester of oxalacetic acid
Synonyms & Antonyms of oxaloacetate
No Synonyms and anytonyms found
oxaloacetate Sentence Examples
- Oxaloacetate, a crucial intermediate in the citric acid cycle, plays a vital role in regulating energy metabolism.
- The enzymatic conversion of phosphoenolpyruvate to oxaloacetate marks the entry point of glycolysis into the Krebs cycle.
- Oxaloacetate can be derived from pyruvate through carboxylation, allowing cells to replenish citric acid cycle intermediates.
- The availability of oxaloacetate dictates the rate of gluconeogenesis, the process of synthesizing glucose from non-carbohydrate precursors.
- Oxaloacetate serves as a substrate for aspartate aminotransferase, linking the citric acid cycle to amino acid metabolism.
- Defects in oxaloacetate metabolism can lead to dysregulation of cellular energy production and various metabolic disorders.
- By controlling the production of oxaloacetate, cells can fine-tune the balance between energy generation and biosynthesis.
- Oxaloacetate participates in the formation of malate, a molecule involved in mitochondrial shuttling.
- The concentration of oxaloacetate within mitochondria influences the production of reactive oxygen species, impacting cellular redox balance.
- Pharmacological modulation of oxaloacetate metabolism holds therapeutic potential for conditions involving mitochondrial dysfunction and metabolic derangements.
FAQs About the word oxaloacetate
a salt or ester of oxalacetic acid
No synonyms found.
No antonyms found.
Oxaloacetate, a crucial intermediate in the citric acid cycle, plays a vital role in regulating energy metabolism.
The enzymatic conversion of phosphoenolpyruvate to oxaloacetate marks the entry point of glycolysis into the Krebs cycle.
Oxaloacetate can be derived from pyruvate through carboxylation, allowing cells to replenish citric acid cycle intermediates.
The availability of oxaloacetate dictates the rate of gluconeogenesis, the process of synthesizing glucose from non-carbohydrate precursors.
