megalocyte (Meaning)
megalocyte (n)
abnormally large red blood cell (associated with pernicious anemia)
megalocyte (n.)
A large, flattened corpuscle, twice the diameter of the ordinary red corpuscle, found in considerable numbers in the blood in profound anaemia.
Synonyms & Antonyms of megalocyte
No Synonyms and anytonyms found
megalocyte Sentence Examples
- The presence of megalocytes in the blood indicates a deficiency in vitamin B12 or folate.
- Macrocytic anemia, characterized by large red blood cells with an oval shape, is often caused by the presence of megalocytes.
- The development of megalocytes is a common result of impaired DNA synthesis during erythrocyte maturation.
- Giant megalocytes, known as macro-ovalocytes, are particularly indicative of severe vitamin B12 deficiency.
- The bone marrow aspirate revealed numerous megalocytes, suggesting a nutritional deficiency.
- Treatment with vitamin B12 supplements can effectively reverse the formation of megalocytes and improve blood counts.
- Megalocytes have an increased fragility compared to normal-sized red blood cells.
- The reticulocyte count, a measure of immature red blood cells, is elevated in conditions with megalocytes.
- Pregnant women are at an increased risk of developing megalocytic anemia due to the increased demand for folate and vitamin B12 during fetal growth.
- The presence of megalocytes can be detected through routine blood tests and examination of the peripheral blood smear.
FAQs About the word megalocyte
abnormally large red blood cell (associated with pernicious anemia)A large, flattened corpuscle, twice the diameter of the ordinary red corpuscle, found in cons
No synonyms found.
No antonyms found.
The presence of megalocytes in the blood indicates a deficiency in vitamin B12 or folate.
Macrocytic anemia, characterized by large red blood cells with an oval shape, is often caused by the presence of megalocytes.
The development of megalocytes is a common result of impaired DNA synthesis during erythrocyte maturation.
Giant megalocytes, known as macro-ovalocytes, are particularly indicative of severe vitamin B12 deficiency.
