ligand (Meaning)
Wordnet
ligand (n)
a substance (an atom or molecule or radical or ion) that forms a complex around a central atom
Synonyms & Antonyms of ligand
No Synonyms and anytonyms found
ligand Sentence Examples
- The ligand binds to the receptor on the cell surface, triggering a signaling cascade.
- The ligand-receptor interaction is highly specific, ensuring that only the correct ligand can bind to a particular receptor.
- The affinity of a ligand for its receptor determines the strength of the binding interaction.
- Ligand binding can induce conformational changes in the receptor protein, leading to downstream signaling events.
- Ligands can be either agonists, which activate the receptor, or antagonists, which block receptor activation.
- The ligand-receptor complex is often internalized into the cell after ligand binding, leading to downregulation of the receptor.
- Ligands play a crucial role in cell-cell signaling, hormone action, and neurotransmission.
- The development of synthetic ligands has led to the discovery of new therapeutic agents for treating diseases.
- Ligand-based drug design focuses on creating molecules that mimic the structure and binding properties of endogenous ligands.
- Ligands form the basis of many biochemical assays used to study protein-ligand interactions and cellular signaling pathways.
FAQs About the word ligand
a substance (an atom or molecule or radical or ion) that forms a complex around a central atom
No synonyms found.
No antonyms found.
The ligand binds to the receptor on the cell surface, triggering a signaling cascade.
The ligand-receptor interaction is highly specific, ensuring that only the correct ligand can bind to a particular receptor.
The affinity of a ligand for its receptor determines the strength of the binding interaction.
Ligand binding can induce conformational changes in the receptor protein, leading to downstream signaling events.