fibroblast (Meaning)
fibroblast (n)
a cell from which connective tissue develops
Synonyms & Antonyms of fibroblast
No Synonyms and anytonyms found
fibroblast Sentence Examples
- Fibroblasts are specialized cells in connective tissue responsible for producing the extracellular matrix, a network of proteins and fibers that provides structural support and a scaffold for tissue growth and repair.
- Fibroblasts are the most abundant cells in the connective tissue, found in various tissues throughout the body, including skin, tendons, ligaments, and internal organs.
- These cells have a flattened, elongated shape and possess prominent nuclei with visible nucleoli.
- They synthesize and secrete various components of the extracellular matrix, including collagen, elastin, and hyaluronic acid, which contribute to tissue strength, elasticity, and hydration.
- Fibroblasts play a crucial role in wound healing, where they migrate to the injury site, proliferate, and produce new extracellular matrix to repair damaged tissue.
- During tissue remodeling and fibrosis, fibroblasts can undergo activation, characterized by increased proliferation, migration, and production of extracellular matrix components, leading to the formation of scar tissue.
- Fibroblasts are involved in maintaining tissue homeostasis by continuously remodeling and repairing damaged extracellular matrix components, ensuring tissue integrity and proper function.
- The activity and function of fibroblasts are influenced by various growth factors, cytokines, and mechanical cues present in the cellular microenvironment.
- Dysregulation of fibroblast function can contribute to various fibrotic diseases, where excessive extracellular matrix accumulation leads to tissue dysfunction and organ damage.
- Researchers are investigating the role of fibroblasts in tissue engineering and regenerative medicine, aiming to harness their ability to produce extracellular matrix components for the development of biomaterials and tissue constructs for repair and regeneration.
FAQs About the word fibroblast
a cell from which connective tissue develops
No synonyms found.
No antonyms found.
Fibroblasts are specialized cells in connective tissue responsible for producing the extracellular matrix, a network of proteins and fibers that provides structural support and a scaffold for tissue growth and repair.
Fibroblasts are the most abundant cells in the connective tissue, found in various tissues throughout the body, including skin, tendons, ligaments, and internal organs.
These cells have a flattened, elongated shape and possess prominent nuclei with visible nucleoli.
They synthesize and secrete various components of the extracellular matrix, including collagen, elastin, and hyaluronic acid, which contribute to tissue strength, elasticity, and hydration.
