fibrinase (Meaning)
fibrinase (n)
in the clotting of blood thrombin catalyzes factor XIII into its active form (fibrinase) which causes fibrin to form a stable clot
Synonyms & Antonyms of fibrinase
No Synonyms and anytonyms found
fibrinase Sentence Examples
- Fibrinase is a crucial enzyme in the coagulation cascade, responsible for converting fibrinogen into fibrin.
- Its primary role is to facilitate blood clot formation by cross-linking fibrin molecules to create a stable fibrin mesh.
- Fibrinase activity is regulated by various factors, including calcium ions, thrombin, and inhibitors such as antithrombin.
- Abnormalities in fibrinase activity can lead to bleeding disorders or thrombosis, depending on whether the enzyme is deficient or excessively active.
- Fibrinase deficiency, a rare bleeding disorder, impairs the body's ability to form stable blood clots, resulting in prolonged bleeding times.
- Conversely, excessive fibrinase activity can cause thrombosis, where clots form abnormally within blood vessels, obstructing blood flow and potentially leading to serious complications.
- Fibrinase inhibitors, such as heparin or warfarin, are commonly used as anticoagulants to prevent or treat thrombosis by reducing fibrinase activity.
- Measuring fibrinase levels and activity is a crucial component of evaluating coagulation disorders and monitoring anticoagulant therapy.
- Genetic mutations in the fibrinase gene can lead to inherited fibrinase disorders, affecting its activity and predisposing individuals to bleeding or clotting disorders.
- Ongoing research is focused on developing new fibrinase-based therapies to improve hemostasis and prevent thrombosis in various clinical settings.
FAQs About the word fibrinase
in the clotting of blood thrombin catalyzes factor XIII into its active form (fibrinase) which causes fibrin to form a stable clot
No synonyms found.
No antonyms found.
Fibrinase is a crucial enzyme in the coagulation cascade, responsible for converting fibrinogen into fibrin.
Its primary role is to facilitate blood clot formation by cross-linking fibrin molecules to create a stable fibrin mesh.
Fibrinase activity is regulated by various factors, including calcium ions, thrombin, and inhibitors such as antithrombin.
Abnormalities in fibrinase activity can lead to bleeding disorders or thrombosis, depending on whether the enzyme is deficient or excessively active.
