5-hydroxy-3-methylglutaryl-coenzyme a reductase (Meaning)

Wordnet

5-hydroxy-3-methylglutaryl-coenzyme a reductase (n)

a liver enzyme that is responsible for producing cholesterol

Synonyms & Antonyms of 5-hydroxy-3-methylglutaryl-coenzyme a reductase

No Synonyms and anytonyms found

5-hydroxy-3-methylglutaryl-coenzyme a reductase Sentence Examples

  1. 5-Hydroxy-3-methylglutaryl-coenzyme A reductase is a key enzyme in the biosynthesis of cholesterol.
  2. Researchers are studying the inhibition of 5-hydroxy-3-methylglutaryl-coenzyme A reductase as a potential target for cholesterol-lowering medications.
  3. The activity of 5-hydroxy-3-methylglutaryl-coenzyme A reductase is tightly regulated in response to cellular cholesterol levels.
  4. Statins are a class of drugs that work by inhibiting 5-hydroxy-3-methylglutaryl-coenzyme A reductase, reducing cholesterol synthesis.
  5. Genetic mutations in the gene encoding 5-hydroxy-3-methylglutaryl-coenzyme A reductase can lead to familial hypercholesterolemia.
  6. The crystal structure of 5-hydroxy-3-methylglutaryl-coenzyme A reductase has been elucidated, providing insights into its catalytic mechanism.
  7. Elevated levels of 5-hydroxy-3-methylglutaryl-coenzyme A reductase activity are associated with increased cholesterol production in certain metabolic conditions.
  8. Pharmaceutical companies are actively researching new compounds that selectively target 5-hydroxy-3-methylglutaryl-coenzyme A reductase for improved cholesterol management.
  9. The expression of 5-hydroxy-3-methylglutaryl-coenzyme A reductase is upregulated in response to low cellular cholesterol, ensuring a feedback mechanism in cholesterol homeostasis.
  10. Understanding the regulation of 5-hydroxy-3-methylglutaryl-coenzyme A reductase is crucial for developing therapeutic interventions for cholesterol-related disorders.

FAQs About the word 5-hydroxy-3-methylglutaryl-coenzyme a reductase

a liver enzyme that is responsible for producing cholesterol

No synonyms found.

No antonyms found.

5-Hydroxy-3-methylglutaryl-coenzyme A reductase is a key enzyme in the biosynthesis of cholesterol.

Researchers are studying the inhibition of 5-hydroxy-3-methylglutaryl-coenzyme A reductase as a potential target for cholesterol-lowering medications.

The activity of 5-hydroxy-3-methylglutaryl-coenzyme A reductase is tightly regulated in response to cellular cholesterol levels.

Statins are a class of drugs that work by inhibiting 5-hydroxy-3-methylglutaryl-coenzyme A reductase, reducing cholesterol synthesis.