hmg-coa reductase Sentence Examples

1. HMG-CoA reductase is the rate-limiting enzyme in the mevalonate pathway, which is responsible for cholesterol synthesis.
2. Inhibition of HMG-CoA reductase is the primary mechanism of action for statins, a class of drugs used to lower cholesterol levels.
3. HMG-CoA reductase is regulated by multiple factors, including insulin, cholesterol levels, and the sterol regulatory element-binding proteins (SREBPs).
4. Mutations in the HMG-CoA reductase gene can lead to familial hypercholesterolemia, a condition characterized by high levels of LDL cholesterol.
5. HMG-CoA reductase inhibitors are a safe and effective treatment for hypercholesterolemia, and they have been shown to reduce the risk of cardiovascular events.
6. The HMG-CoA reductase pathway is also involved in the synthesis of other isoprenoids, such as ubiquinone and dolichol.
7. HMG-CoA reductase is a key enzyme in cholesterol metabolism, and its inhibition is an important therapeutic strategy for reducing cholesterol levels.
8. The expression of HMG-CoA reductase is regulated by various transcription factors, including SREBP-2 and LXR.
9. HMG-CoA reductase inhibitors are generally well-tolerated, with the most common side effects being muscle pain and gastrointestinal upset.
10. The development of HMG-CoA reductase inhibitors has been a major breakthrough in the treatment of hypercholesterolemia and has significantly reduced the risk of cardiovascular events.

hmg-coa reductase Meaning

Wordnet

hmg-coa reductase (n)

a liver enzyme that is responsible for producing cholesterol

Synonyms & Antonyms of hmg-coa reductase

No Synonyms and anytonyms found

FAQs About the word hmg-coa reductase

What is the meaning of the word hmg-coa reductase

a liver enzyme that is responsible for producing cholesterol

What are the synonyms of the word hmg-coa reductase

No synonyms found.

What are the antonyms of the word hmg-coa reductase

No antonyms found.

What is the usage of word hmg-coa reductase

HMG-CoA reductase is the rate-limiting enzyme in the mevalonate pathway, which is responsible for cholesterol synthesis.

Inhibition of HMG-CoA reductase is the primary mechanism of action for statins, a class of drugs used to lower cholesterol levels.

How to use the word hmg-coa reductase in a sentence?

HMG-CoA reductase is regulated by multiple factors, including insulin, cholesterol levels, and the sterol regulatory element-binding proteins (SREBPs).

Mutations in the HMG-CoA reductase gene can lead to familial hypercholesterolemia, a condition characterized by high levels of LDL cholesterol.